Atıf İçin Kopyala
Pinarli F. A., Okten G., Beden U., Fisgin T., Kefeli M., Kara N., ...Daha Fazla
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, cilt.7, sa.2, ss.211-219, 2014 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
7
Sayı:
2
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Basım Tarihi:
2014
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Doi Numarası:
10.3980/j.issn.2222-3959.2014.02.05
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Dergi Adı:
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.211-219
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Anahtar Kelimeler:
corneal wound healing, mesenchymal stem cells, keratinocyte growth factor-2, autologous serum, amniotic membrane, TRANSPLANTATION, RECONSTRUCTION, MODEL, DIFFERENTIATION, EPITHELIUM, THERAPY, SURFACE
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Ondokuz Mayıs Üniversitesi Adresli:
Evet
Özet
AIM: To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells (MSCs) cultured with or without keratinocyte growth factor (KGF -2) and autologous serum (AS) on amniotic membrane (AM). Many patients are blind and devastated by severe ocular surface diseases due to limbal stem cell deficiency. Bone marrow -derived MSCs are potential sources for cell - based tissue engineering to repair or replace the corneal tissue, having the potential to differentiate to epithelial cells.