The effect of surgical denervation on prevention of excessive dermal scarring: A study on rabbit ear hypertrophic scar model

Yagmur C., Guneren E., Kefeli M., Ogawa R.

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, cilt.64, sa.10, ss.1359-1365, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 10
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.bjps.2011.04.028
  • Dergi Adı: JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1359-1365
  • Anahtar Kelimeler: Hypertrophic scar, Keloid, Nerve, Denervation, Sensory denervation, Mechanosensitive nociceptor, Neuropeptide, Neurogenic inflammation, Substance P, Free nerve ending, Axon reflex, GENE-RELATED PEPTIDE, SENSORY DENERVATION, WOUND CONTRACTION, SUBSTANCE-P, RAT SKIN, INHIBITION, QUANTIFICATION, PROLIFERATION, INFLAMMATION, INNERVATION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Previous reports have suggested that the extent of wound contraction, epithelisation and total healing time were influenced by denervation of tissues. In this article, we studied for the first time the effect of sensory denervation on prevention of excessive dermal scarring. Materials and