Intracerebroventricular Application of Dexmedetomidine Produces Antinociception and Does not Cause Neurotoxicity in Rats

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Köksal E., Karakaya D., Can Meydan B., Bozkurt A., Barış S., Bilge S. S., ...Daha Fazla

BALKAN MEDICAL JOURNAL, cilt.30, sa.4, ss.355-361, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5152/balkanmedj.2013.7747
  • Dergi Adı: BALKAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.355-361
  • Anahtar Kelimeler: Dexmedetomidine, analgesia, neurotoxicity, CLONIDINE, BUPIVACAINE, RECEPTOR, ANALGESIA, AGONISTS, COMPLICATIONS, PHARMACOLOGY, ANTAGONIST, BLOCKADE, EFFICACY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Alpha 2 agonists contribute to pain control at the level of the medulla spinalis. Alpha 2 agonists are generally added to local anaesthetics to prolong spinal or epidural anaesthesia time.