Anesthetic Management of a Pediatric Patient with Leigh Syndrome

Kocamanoğlu İ. S., Sarihasan E.

REVISTA BRASILEIRA DE ANESTESIOLOGIA, cilt.63, sa.2, ss.220-222, 2013 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/s0034-7094(13)70219-8
  • Dergi Adı: REVISTA BRASILEIRA DE ANESTESIOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.220-222
  • Anahtar Kelimeler: Leigh Disease, Anesthesia, General, Monitoring, Physiologic, Intensive Care
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background and objectives: Leigh syndrome (LS) is a rare disease caused by abnormalities of mitochondrial energy generation. The central nervous system is most frequently affected, with psychomotor underdevelopment, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Surgical and anesthetic procedures stimulate the tracheal irritability, and could exacerbate risks of aspiration, wheezing, breathing difficulties, gasping, hypoventilation, and apnea.