The assessment of the serum levels of TWEAK and prostaglandin F2 alpha in COVID-19

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YALÇIN KEHRİBAR D., Cihangiroglu M., Sehmen E., Avcı B., Capraz M., Boran M., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.50, sa.8, ss.1786-1791, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 8
  • Basım Tarihi: 2020
  • Doi Numarası: 10.3906/sag-2006-96
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1786-1791
  • Anahtar Kelimeler: COVID-19, TWEAK, leukotrienes, inflammation, prostaglandin, WEAK INDUCER, CYTOKINE, RECEPTOR, PATHWAY, LUPUS, MONTELUKAST, INDUCTION, APOPTOSIS, DISEASE
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background/aim: It is claimed that aberrant immune response has a more important role than the cytopathic effect of the virus in the morbidity and mortality of the coronavirus disease 2019 (COVID-19). We aimed to investigate the possible roles of tumor necrosis factor-like weak inducer of apoptosis (TWEA K)/Fn14 pathway and leukotrienes (LT) in uncontrolled immune response that occurs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).