Lifesaving dose increment of cabergoline in life-threatening spontaneous ovarian hyperstimulation syndrome resistant to all interventions

Celik S., Soyer-Caliskan C., Hatirnaz S., Çelik H., TOSUN M., Hatirnaz E. S.

GYNECOLOGICAL ENDOCRINOLOGY, cilt.35, sa.4, ss.287-289, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/09513590.2018.1525703
  • Dergi Adı: GYNECOLOGICAL ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.287-289
  • Anahtar Kelimeler: Spontaneous ovarian hyperstimulation syndrome, singleton pregnancy, pregnancy termination, cabergoline, DOPAMINE AGONIST CABERGOLINE, ASSISTED REPRODUCTION, WOMEN, STIMULATION, MUTATION, RECEPTOR, PREVENT, TORSION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: Spontaneous ovarian hyperstimulation syndrome (SOHSS) is an extremely rare complication that deserves a multidisciplinary approach together with a thorough investigation for the correct diagnosis of the underlying pathology. The aim of this study was to present a case of severe SOHSS resistant to all interventions and to discuss the available interventions to overcome such a rare and serious clinical situation. Case report: We report a case of severe, life-threatening spontaneous OHSS with a normal nine weeks singleton pregnancy in a 25-year-old nulliparous woman, which resulted with pregnancy termination and continuation of disease progression until the dose of cabergoline was increased to 1.5 mg/day. Conclusion: This case report emphasizes that patients with life-threatening SOHSS resistant to all medical and surgical interventions may benefit from higher doses of cabergoline. Although spontaneous OHSS is extremely rare, it is potentially a life-threatening clinical entity in its severe form and needs time management and detailed examination of the underlying causes.