Amyloid goiter: two cases and a review of the literature

Yıldız L., Kefeli M., Kose B., Baris S.

ANNALS OF SAUDI MEDICINE, cilt.29, sa.2, ss.138-141, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.4103/0256-4947.51808
  • Dergi Adı: ANNALS OF SAUDI MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.138-141
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Although involvement of the thyroid gland by amyloid is a relatively common phenomenon, clinically significant enlargement of the thyroid owing to amyloid deposition is an extremely rare occurrence. We describe two cases of amyloid goiter and review the relevant literature. The first case was systemic amyloidosis secondary to familial Mediterranean fever. The second case was a chronic renal failure patient who presented with an enlarged thyroid and upper airway obstructive symptoms. To date, true amyloid goiter secondary to amyloidosis associated with familial Mediterranean fever has only been reported in twelve patients.