Atıf İçin Kopyala
Sumer A. P., Kara N., Keles G. C., Güneş S., Koprulu H., Bagci H.
JOURNAL OF PERIODONTOLOGY, cilt.78, sa.3, ss.493-497, 2007 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
78
Sayı:
3
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Basım Tarihi:
2007
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Doi Numarası:
10.1902/jop.2007.060309
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Dergi Adı:
JOURNAL OF PERIODONTOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.493-497
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Anahtar Kelimeler:
chronic periodontitis, cytokines, genetic polymorphism, interleukin-10, periodontal disease, PROMOTER POLYMORPHISMS, JAPANESE PATIENTS, VITAMIN-D, RISK-FACTORS, DISEASE, IL-10, PROGRESSION, ALLELE, ADULT
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Ondokuz Mayıs Üniversitesi Adresli:
Evet
Özet
Background: Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a role in periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating protective antibody production. Genetic polymorphisms in the IL-10 gene might be useful as a marker to diagnose susceptibility to periodontitis. Therefore, the aim of this study was to investigate the association between IL-10 gene polymorphisms and severe generalized chronic periodontitis (CP) in a Turkish population.