The effectiveness of combined preventive treatment with Ceftiofur, Oxytocin and PGF(2 alpha) on fertility parameters in cows

Kaya D., Ay S. S., Kucukaslan I., Beceriklisoy H. B., Agaoglu A. R., FINDIK M., ...Daha Fazla

REVUE DE MEDECINE VETERINAIRE, cilt.163, sa.6, ss.302-308, 2012 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 163 Sayı: 6
  • Basım Tarihi: 2012
  • Dergi Adı: REVUE DE MEDECINE VETERINAIRE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.302-308
  • Anahtar Kelimeler: Postpartum cows, preventive treatment, fertility, RETAINED FETAL MEMBRANES, SYSTEMIC ANTIBIOTIC-TREATMENT, POSTPARTUM UTERINE DISEASE, POST-PARTUM PERIOD, REPRODUCTIVE-PERFORMANCE, DAIRY-COWS, CLINICAL ENDOMETRITIS, INVOLUTION, PROSTAGLANDIN-F2-ALPHA, METRITIS
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

The present study is aimed at evaluating the effectiveness of combined preventive treatment with Ceftiofur Hydrochloride (CHR), Oxytocin (OXT) and PGF(2 alpha) on fertility parameters and puerperal disorder rates in postpartum (pp) dairy cows. A total of 191 Holstein-Friesian cows were divided into four groups. The cows in group I (GI; n=37) and II (GII; n=69) were treated on a daily basis with CHR and OXT for five and three days pp, respectively. Group III (GIII; n=52) was designed as the PGF(2 alpha) group, and group IV (GIV; n=33) served as a control group. The animals in GI, GII, and Gill were given a PGF(2 alpha) analogue on days 15 and 26 pp. Each group was further divided into subgroups of normal parturition (np) and dystocia (d) when the study results were evaluated. It was found that the first service pregnancy rates for the subgroup of dystocia were significantly higher (P<0.05 and P<0.01) in subgroup GII (76.9%) than in GI (30.0%) and GIV (37.5%). Furthermore, the median time to first service and the median time to pregnancy were longer for cows in subgroup GIVd as compared with subgroups GId, GIId, and GIIId (P<0.001; P<0.01). Group II was found to have the lowest endometritis rates after treatment of subgroups-d and -np. No statistically significant difference was found between the groups with regard to cystic ovary rates after treatment (P>0.05). As the treatment with CHR-OXT combined with PGF(2 alpha) on days 15 and 26 was associated to improved uterine involution patterns and reproductive performance, our results suggest that administration of this preventive treatment would be useful, especially for cases of dystocia.