Effects of mobile phone exposure on metabolomics in the male and female reproductive systems

Altun G., Deniz O. G., Yurt K. K., Davis D., Kaplan S.

ENVIRONMENTAL RESEARCH, cilt.167, ss.700-707, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 167
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.envres.2018.02.031
  • Dergi Adı: ENVIRONMENTAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.700-707
  • Anahtar Kelimeler: Mobile phone exposure, Oxidative stress, Spermatogenesis, Oogenesis, MHZ ELECTROMAGNETIC-FIELD, WHOLE-BODY EXPOSURE, LONG-TERM EXPOSURE, OXIDATIVE STRESS, CELL PHONE, SEMEN QUALITY, RAT TESTIS, MALE-INFERTILITY, WI-FI, RADIOFREQUENCY RADIATION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

With current advances in technology, a number of epidemiological and experimental studies have reported a broad range of adverse effects of electromagnetic fields (EMF) on human health. Multiple cellular mechanisms have been proposed as direct causes or contributors to these biological effects. EMF-induced alterations in cellular levels can activate voltage-gated calcium channels and lead to the formation of free radicals, protein misfolding and DNA damage. Because rapidly dividing germ cells go through meiosis and mitosis, they are more sensitive to EMF in contrast to other slower-growing cell types. In this review, possible mechanistic pathways of the effects of EMF exposure on fertilization, oogenesis and spermatogenesis are discussed. In addition, the present review also evaluates metabolomic effects of GSM-modulated EMFs on the male and female reproductive systems in recent human and animal studies. In this context, experimental and epidemiological studies which examine the impact of mobile phone radiation on the processes of oogenesis and spermatogenesis are examined in line with current approaches.