Cardioprotective effect of aminoguanidine in combination with steroid therapy after blunt chest trauma

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Duran L., Guzel A., Akdemir H. U., Demir F., Karadeniz C., Alacam H., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.115, sa.9, ss.538-543, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 115 Sayı: 9
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4149/bll_2014_104
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.538-543
  • Anahtar Kelimeler: cardiac contusion, blunt chest trauma, iNOS, Bcl-2, methylprednisolone, aminoguanidine, CARDIAC TROPONIN-T, MYOCARDIAL-INFARCTION, LUNG CONTUSION, INJURY, ISCHEMIA, REPERFUSION, RATS, METHYLPREDNISOLONE, MODEL, INFLAMMATION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Cardiac contusion is an important cause of mortality after blunt chest trauma (BCT). The aim of this study was to investigate the therapeutic efficacy of the usage of aminoguanidine (AG), in myocardial damage occurring after BCT, alone and in combination with methylprednisolone (MP).