Evaluation of Nerve Conduction Studies in Obese Children With Insulin Resistance or Impaired Glucose Tolerance

Ince H., Tasdemir H. A., Aydin M., Ozyurek H., Erdem Tilki H.

JOURNAL OF CHILD NEUROLOGY, cilt.30, sa.8, ss.989-999, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 8
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1177/0883073814550188
  • Dergi Adı: JOURNAL OF CHILD NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.989-999
  • Anahtar Kelimeler: peripheric neuropathy, obesity, children, insulin resistance, impaired glucose tolerance, sympathetic skin response, SYMPATHETIC SKIN-RESPONSE, RR INTERVAL VARIATION, MEDIAL PLANTAR NERVE, SURAL NERVE, IDIOPATHIC NEUROPATHY, SENSORY NEUROPATHIES, FIBER INVOLVEMENT, SENSITIVITY, UTILITY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

The aim of the study was to investigate nerve conduction studies in terms of neuropathic characteristics in obese patients who were in prediabetes stage and also to determine the abnormal findings. The study included 69 obese adolescent patients between April 2009 and December 2010. All patients and control group underwent motor (median, ulnar, tibial, and peroneal) and sensory (median, ulnar, sural, and medial plantar) nerve conduction studies and sympathetic skin response test. Sensory response amplitude of the medial plantar nerve was significantly lower in the patients with impaired glucose tolerance and insulin resistance. To our knowledge, the present study is the first study demonstrating the development of sensory and autonomic neuropathy due to metabolic complications of obesity in adolescent children even in the period without development of diabetes mellitus. We recommend that routine electrophysiological examinations be performed, using medial plantar nerve conduction studies and sympathetic skin response test.