Association of matrix metalloproteinase-9 promoter gene polymorphism with chronic periodontitis

Keles G. C., Güneş S., Sumer A. P., Sumer M., Kara N., Bagci H., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.77, sa.9, ss.1510-1514, 2006 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 9
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1902/jop.2006.050378
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1510-1514
  • Anahtar Kelimeler: chronic periodontitis, gelatinase, matrix metalloproteinase-9, polymorphism, GINGIVAL CREVICULAR FLUID, LOCALIZED JUVENILE PERIODONTITIS, GELATINASE B-GENE, MATRIX METALLOPROTEINASES, FUNCTIONAL POLYMORPHISM, TISSUE INHIBITORS, JAPANESE PATIENTS, VITAMIN-D, EXPRESSION, DISEASE
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Matrix metalloproteinases (MMPs) are related to tissue destruction and remodeling events in periodontal diseases. A single nucleotide polymorphism in the promoter region of human MMP-9 gene is associated with the risk of some inflammatory diseases. Therefore, the aim of this study was to investigate the association between MMP-9 promoter polymorphism and severe generalized chronic periodontitis in a Turkish population.