An Unbiased Way to Estimate Total Quantities: The Fractionator Technique

Kaplan S., Canan S., Altunkaynak M. E., Odaci E., Aslan H., Unal B.

NEUROQUANTOLOGY, cilt.10, sa.1, ss.54-65, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 1
  • Basım Tarihi: 2012
  • Dergi Adı: NEUROQUANTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.54-65
  • Anahtar Kelimeler: Cell number, fractionator technique, tissue, neuroscience, STEREOLOGICAL METHODS, PATHOLOGICAL RESEARCH, OPTICAL FRACTIONATOR, ARBITRARY PARTICLES, COUNTING NEURONS, TOTAL NUMBER, DISECTOR, HIPPOCAMPUS, PREDICTION, EFFICIENCY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

The fractionator is a straightforward and unbiased method to estimate virtually any type of total quantity using sectional profiles of tissue particles. Its basic principle and ease of use make this approach is a method of choice in many microscopical quantitative studies. In this review, we will summarize the basic principles of the fractionator approach and give some examples focused especially on some basic topics in neuroscience research.