Effects of Tacrolimus and Nifedipine, Alone or in Combination, on Gingival Tissues

Pamuk F., Özkan Çetinkaya B., Gülbahar M. Y., Gacar A., Keles G. C., Erisgin Z., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.84, sa.11, ss.1673-1682, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 84 Sayı: 11
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1902/jop.2013.120545
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1673-1682
  • Anahtar Kelimeler: Gingival overgrowth, immunohistochemistry, nifedipine, PTEN protein, tacrolimus, RENAL-TRANSPLANT RECIPIENTS, CYCLOSPORINE-A, TUMOR-SUPPRESSOR, NEGATIVE REGULATION, PTEN PHOSPHATASE, OVERGROWTH, EXPRESSION, RATS, HYPERPLASIA, INHIBITION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: The aim of this study is to compare gingival changes induced by short-and long-term tacrolimus and nifedipine administration, alone or in combination, and evaluate the expression levels of tumor suppressor phosphatase and tensin homolog (PTEN) in drug-induced gingival over-growth.