Comparative Evaluation of Adhesions to Intraperitoneally Placed Fixation Materials: A Laparoscopic Study in Rats

Creative Commons License

Gungor B. B., Malazgirt Z., Topgul K., Gok A., Bilgin M., YÜRÜKER S. S.

INDIAN JOURNAL OF SURGERY, cilt.72, sa.6, ss.475-480, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 6
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1007/s12262-010-0168-3
  • Dergi Adı: INDIAN JOURNAL OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.475-480
  • Anahtar Kelimeler: Ventral hernia, Laparoscopic ventral hernia repair, Mesh repair, Intra-abdominal adhesion, Mesh fixation, HERNIA REPAIR, MESH FIXATION, ABDOMINAL ADHESIONS, POLYPROPYLENE MESH, PORCINE MODEL, SPIRAL TACKS, PREVENTION, STRENGTH, INGROWTH, ACID
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

After laparoscopic ventral hernia repair, the nature of the adhesions to fixation materials or to mesh had not been clarified. We examined adhesion formation specific to the fixation material in rats. We designed an experimental laparoscopy setup, and placed four intraperitoneal fixation materials on the peritoneum of rats without a mesh graft. Another group of researchers documented the incidence and intensity of postoperative adhesion formation. The adhesion scores for the nickel-titanium anchor were significantly greater than those for polylactic acid (p = 0.004), a titanium tacker (p < 0.0001), and fibrin glue (p < 0.0001). No adhesions occurred in the fibrin glue group. Fibrin glue is the preferred fixation material because it produced no postoperative adhesions. The nickel-titanium anchor produced heavy adhesions but may be applicable for recurrent hernia cases and in patients with thin abdominal walls.