Evaluation of Extramedullary Plasmacytoma of the Larynx with Radiologic and Histopathological Findings Evaluación del plasmocitoma extramedular de laringe con hallazgos radiológicos e histopatológicos

Sayit A. T., Elmalı M., GÜN S.

Radiologia, cilt.64, sa.1, ss.69-73, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.rx.2020.07.006
  • Dergi Adı: Radiologia
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.69-73
  • Anahtar Kelimeler: Computed tomography, Extramedullary, Larynx, Solitary plasmacytoma
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm of soft tissue without bone marrow involvement or other systemic characteristics of multiple myeloma. Approximately 80-90% of EMPs involve the head and neck region, especially in the nasal cavity, paranasal sinuses, tonsillar fossa, and oral cavity. An EMP of the larynx is extremely rare and is a locally destructive lesion without systemic spread. Clinical features vary depending on the tumor location. A diagnosis is established by histopathology, immunohistochemistry, and a systemic survey to exclude systemic plasma cell proliferative diseases. Extramedullary plasmacytomas are highly radiosensitive and radiotherapy is therefore used as a treatment. In this study, we report on a rare case of EMP of the larynx evaluated with computed tomography and present histopathologic findings for a 74-year-old female patient.