Presepsin (sCD14-ST) as a biomarker of sepsis in clinical practice and in emergency department: a mini review

ERENLER A. K., Yardan T.

LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE, cilt.39, sa.6, ss.367-372, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 39 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1515/labmed-2015-0072
  • Dergi Adı: LABORATORIUMSMEDIZIN-JOURNAL OF LABORATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.367-372
  • Anahtar Kelimeler: diagnostic value, presepsin, sepsis, SOLUBLE CD14 SUBTYPE, DISSEMINATED INTRAVASCULAR COAGULATION, BACTERIAL-INFECTION, DIAGNOSTIC-ACCURACY, SEPTIC SHOCK, MULTICENTER, PREDICTION, MARKER, PROGNOSIS, SEVERITY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Presepsin is a 13-kDa protein that is a fragment of CD14 with truncated N-terminal, the receptor for lipopolysaccharide (LPS)/LPS-binding protein complexes. It is a novel marker being sought in many diseases such as sepsis, kidney failure, disseminated intravascular coagulation, etc. In this review, we aimed to clarify its utility in critical diseases and availability in critical care settings such as emergency departments and intensive care units.