Akademik Veri Yönetim Sistemi
Erciyes Üniversitesi Veteriner Fakültesi Dergisi, cilt.17, sa.2, ss.173-179, 2020 (Hakemli Dergi)
Aflatoxin B1 (AFB1) is an Aspergillus spp. produced mycotoxins which is identified as one of the key con-taminant of feeds and toxic to some degree to all species tested to date. Because of its hepatocarcinogenic nature, AFB1 has obtained significant attention in past few years. A number of analytical, diagnostic and immunological proce-dures are available for assessment and estimation of AFB1 in different feeds such as enzyme linked immunosorbent assay (ELISA), thin layer chromatography (TLC), high performance liquid chromatography (HPLC), liquid chromatog-raphy tandem mass spectrometry (LC-MS/MS) and electrochemical immunosensors (ECI). All available analytical methods for determination of AFB1 principally included the same steps like, sampling, sample preparation, detection, confirmation, and finally risk assessment. HPLC approaches are most commonly used nowadays because of their high accuracy, precision and sensitivity. Since late 20th century, many countries including Turkey has imposed strict rules and regulations regarding AFB1 in food and animal feed related industry to protect the consumer from the detrimental effects of the toxin. In this article, a number of analytical techniques for determination of AFB1 in feeds and feedstuffs starting from sampling to risk assessment and international regulations are reviewed.