A Case of Acute Generalised Exanthematous Pustulosis Induced by Paracetamol

Kutlug S., Celiksoy M. H., Eroglu B., Yıldız L., Yıldıran A.

ASIM ALLERJI IMMUNOLOJI, cilt.15, sa.1, ss.49-54, 2017 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.21911/aai.5007
  • Dergi Adı: ASIM ALLERJI IMMUNOLOJI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.49-54
  • Anahtar Kelimeler: Drug allergy, paracetamol, child, TOXIC EPIDERMAL NECROLYSIS, ADVERSE DRUG-REACTIONS, AGEP
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Acute generalized exanthematous pustulosis is an exanthematous disease characterized by a great number of pustules on an acutely erythematous and edematous surface on the skin. These pustules are smaller than 5 mm, have non-follicular localization, and are sterile and superficial. Drugs are held responsible for 90% of the cases and antibiotics are the main culprits. Viral infections, mercury exposure, spider bite and radiation have also been rarely reported as the causative agent. The mortality of AGEP, which is considered to be one of the Severe Cutaneous Adverse Reactions (SCAR), is 5%. Many of the cases reported are adults. Since AGEP is rare in children, we present a ten-month-old boy who developed AGEP after paracetamol use.