Association between NOS3 intron 4 VNTR variant and sports performance

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Ünver Ş., Atan T., NURSAL A. F., YİĞİT S.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.13, sa.2, ss.225-229, 2022 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4328/acam.20987
  • Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.225-229
  • Anahtar Kelimeler: Nitric Oxide, ENOS, Sports Performance, VNTR, PCR, OXIDE SYNTHASE GENE, NITRIC-OXIDE, BLOOD-PRESSURE, ENOS GENE, POLYMORPHISM, EXERCISE, GENOTYPE, T/C
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Aim: Evidence shows the involvement of Nitric oxide (NO) in glucose metabolism, which is glucose uptake in human skeletal muscle at the time of exercise, controlling function and structure of skeletal muscle, conversion of skeletal muscle fiber type, production of mitochondrial ATP, and uptake of oxygen in skeletal muscles, all necessary for anaerobic and aerobic performance. Endothelial nitric oxide synthase (NOS3) enzyme synthesizes NO. The main purpose of this study was to investigate whether the NOS3 gene variable number of tandem repeats (VNTR) variant affected athletic performance in the Turkish population.