Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT

Creative Commons License

Canbaz Tosun F., Aydın H. M., Can Meydan B., Ceyhan Bilgici M. N., Ariturk E.

MOLECULAR IMAGING AND RADIONUCLIDE THERAPY, cilt.28, sa.2, ss.83-85, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 28 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/mirt.galenos.2018.38039
  • Dergi Adı: MOLECULAR IMAGING AND RADIONUCLIDE THERAPY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.83-85
  • Anahtar Kelimeler: Nesidioblastosis, hyperinsulinemic hypoglycemia, differential diagnosis, Ga-68 DOTATATE PET/CT, HYPERINSULINISM, LOCALIZATION, CHILDREN
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

"Nesidioblastosis", later renamed as "persistent hyperinsulinemic hypoglycemia of infancy" presents as either focal or diffuse neo-differentiation of pancreatic Langerhans islet cells from the ductal epithelium. Differentiation of focal disease from diffuse involvement is crucial for optimal disease management. The current methods used to differentiate the two forms pre-operatively are invasive techniques. The definite role of imaging modalities to differentiate diffuse versus focal form has not yet been proven. Herein, we report a 15 day-old infant having diffuse nesidioblastosis, successfully demonstrated by Ga-68 DOTATATE positron emission tomography/computed tomography imaging that was histopathologically confirmed.