The effect of low dose aspirin intake on gastro-duodenal mucosa, and protective effects of GSH-vitamin C-E

Aydogan S., AMANVERMEZ R.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.37, sa.3, ss.322-328, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5505/tjb.2012.20592
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.322-328
  • Anahtar Kelimeler: Low dose aspirin, gastro-duodenal pathology, antioxidants, oxidative stress, OXIDATIVE STRESS, INJURY, RATS, INFLAMMATION, PROTEINS, THERAPY, HUMANS, DAMAGE, RISKS, SHOCK
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objectives: Neutrophil-mediated inflammation and oxidative stress may be the important events that lead to gastroduodenal mucosal damage induced by aspirin. It is hypothesized that GSH-vitamin C-E may protect to the upper gastrointestinal mucosa against low dose aspirin's (L-ASA) adverse effects.