Stereological evaluation of the volume and volume fraction of intracranial structures in magnetic resonance images of patients with Alzheimer's disease

Bas O., Acer N., Mas N., Karabekir H. S., YILMAZ KÜSBECİ Ö., Şahin B.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, cilt.191, sa.2, ss.186-195, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 191 Sayı: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.aanat.2008.12.003
  • Dergi Adı: ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.186-195
  • Anahtar Kelimeler: Cavalieri principle, Volume estimation, Volume ratio, Magnetic resonance imaging, Stereology, Alzheimer, TEMPORAL-LOBE, CAVALIERI PRINCIPLE, NORMATIVE VALUES, CEREBRAL ATROPHY, LIVER VOLUME, SERIAL MRI, MORPHOLOGY, CARCINOMA, COMBINATION, MORPHOMETRY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

In this study, we describe and adapt the relevant methods of magnetic resonance (MR) and stereology to estimate total brain volume (TBV), cerebral and cerebellar volume and their volume fractions within the brain. The study included 15 (8 males, 7 females) controls and 15 (8 males, 7 females) patients with Alzheimer's disease. The patients MR images were obtained in both sagittal and axial planes. The volume and volume fraction of the total brain, cerebrum and cerebellum were determined on MR images using the point-counting approach of stereological methods.