Disseminated Panton-Valentine Leukocidin-Positive Staphylococcus aureus infection in a child

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Karli A., Yanik K., Paksu M. S., Sensoy G., Aykanat A., Yener N., ...Daha Fazla

ARCHIVOS ARGENTINOS DE PEDIATRIA, cilt.114, sa.2, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 114 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5546/aap.2016.eng.e75
  • Dergi Adı: ARCHIVOS ARGENTINOS DE PEDIATRIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Staphylococcus aureus, Panton-Valentine leukocidin, necrotizing pneumonia, sepsis, METHICILLIN-RESISTANT, PNEUMONIA, SKIN
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Panton-Valentine leukocidin (PVL) is an exotoxin that is produced by many strains of Staphylococcus aureus, and an important virulence factor. A PVL-positive S. aureus infection leads to rapid and severe infections of soft tissue and necrotizing pneumonia in healthy adolescents, and has a high mortality. This case report included a 12-year-old male patient who admitted for fever, respiratory distress and hip pain and was identified with necrotizing pneumonia with septic pulmonary embolism, psoas abscess, cellulitis and osteomyelitis. The PVL positive methicillin-sensitive S. aureus (MSSA) was isolated in the patient blood culture.