Acneiform skin lesions associated with cetuximab therapy: Report of two cases


Yilmaz Ö., Özden M. G., Aydın F., Şentürk N., Cantürk T., Turanli A. Y.

Journal of Experimental and Clinical Medicine (Turkey), cilt.27, sa.3, ss.118-119, 2010 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2010
  • Doi Numarası: 10.5835/jecm.omu.27.03.004
  • Dergi Adı: Journal of Experimental and Clinical Medicine (Turkey)
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.118-119
  • Anahtar Kelimeler: Acneiform eruption, Cetuximab, Chemotherapy, Colorectal cancer, Irinotecan, Side effect
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Cetuximab, is an IgG1 chimeric monoclonal antibody type of epidermal growth factor receptor (EGFR). It is most commonly prescribed for metastatic colorectal cancer, administered alone or in combination with irinotecan-based chemotherapy regimens (Lee et al., 2008; Segaert et al., 2005; Segaert and Cutsem 2005; Scope et al., 2009). Acneiform eruption is the most common adverse effect with 80% of incidence (Segaert and Cutsem 2005; Lee et al., 2008). We report two cases of severe acneiform eruption induced by cetuximab with metastatic colorectal cancer. © 2010 OMU All rights reserved.