Evaluation of apoptotic cell death on liver and kidney tissues following administration of levetiracetam during prenatal period

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Atıf İçin Kopyala

TEKCAN A., Tural Ş., Elbistan M., Güvenç T., Ayas B., Kara N.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, cilt.30, sa.4, ss.420-423, 2017 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 30 Sayı: 4
• Basım Tarihi: 2017
• Doi Numarası: 10.1080/14767058.2016.1174990
• Dergi Adı: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.420-423
• Anahtar Kelimeler: Apoptosis, kidney, levetiracetam, liver, prenatal exposure, TUNEL assay, EPILEPSY, PREGNANCY, WOMEN, LYMPHOCYTES, MANAGEMENT, INJURY, RISKS, DRUGS
• Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: Levetiracetam is a new generation antiepileptic drug used in treatment of patients with epilepsy and has adverse effects on different tissues. We aimed to evaluate the apoptotic effects of levetiracetam exposure during pregnancy on liver and kidney tissues of rat pups.