Is Symptomatic Atherosclerotic Cerebrovascular Disease a Risk Factor for Normal-Tension Glaucoma?

Gungor I. U., Gungor L., Ozarslan Y., Arıtürk N., Beden U., Erkan D., ...Daha Fazla

MEDICAL PRINCIPLES AND PRACTICE, cilt.20, sa.3, ss.220-224, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1159/000323596
  • Dergi Adı: MEDICAL PRINCIPLES AND PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.220-224
  • Anahtar Kelimeler: Normal-tension glaucoma, Glaucomatous optic neuropathy, Cerebral atherosclerosis, Cerebrovascular diseases, OPEN-ANGLE GLAUCOMA, OPTIC-NERVE HEAD, CAUSATIVE CLASSIFICATION, ISCHEMIC-STROKE, BLOOD-FLOW, PROGRESSION, PRESSURE, SYSTEM
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: To compare the incidence of glaucomatous optic disk appearance between patients with symptomatic atherosclerotic stroke and healthy individuals with normal intraocular pressures (IOP). Subjects and Methods: 46 patients with ischemic stroke with evident lacunar infarction or large vessel atherosclerosis, and 93 age-and sex-matched healthy individuals, all with normal IOP, were included. Patients and controls were examined for the presence of high cup-to-disk ratios (> 0.5). Results: Seven patients (15.22%) in the ischemic cerebrovascular disease (CVD) group and 3 controls (3.23%) had glaucomatous optic disk appearance. All subjects with glaucomatous optic disk appearance in the control group and 3 patients in the study group had visual field defects in concordance with normal-tension glaucoma (NTG). The incidence of glaucomatous optic disk appearance was significantly higher in the group with symptomatic atherosclerotic CVD. Conclusion: Atherosclerotic CVD is a risk factor for having glaucomatous optic disk appearance. Symptomatic atherosclerosis involving the brain vasculature may also affect the eye and lead to NTG. Patients with ischemic strokes due to large artery atherosclerosis or small artery occlusion must be examined and followed for NTG. Copyright (C) 2011 S. Karger AG, Basel