The effect of pentoxifylline on venous flap survival

Eroǧlu L., Karacaoǧlan N., Uysal O.

European Journal of Plastic Surgery, cilt.24, sa.4, ss.169-171, 2001 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1007/s002380100263
  • Dergi Adı: European Journal of Plastic Surgery
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.169-171
  • Anahtar Kelimeler: Pentoxifylline, Venous flap
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

An experimental study was performed to determine whether the survival area of a flap can be increased using pentoxifylline in a single-pedicled venous skin flap in the rat. Epigastric island venous skin flaps measuring 1.5×2.5 cm were constructed bilaterally. The experimental group received intraperitoneal injections of pentoxifylline 25 mg/kg daily for 7 days following the operation. This study shows the pentoxifylline had no beneficial effect on single-pedicled venous island skin flap viability in the rat model.