An evaluation of false-positive rifampicin resistance on the Xpert MTB/RIF

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Tanrıverdi Çaycı Y., BİLGİN K., Coban A. Y., Birinci A., Durupinar B.

MEMORIAS DO INSTITUTO OSWALDO CRUZ, cilt.112, sa.11, ss.756-759, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 112 Sayı: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1590/0074-02760170051
  • Dergi Adı: MEMORIAS DO INSTITUTO OSWALDO CRUZ
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.756-759
  • Anahtar Kelimeler: Mycobacterium tuberculosis, rifampicin resistance, Xpert MTB/RIF assay, MYCOBACTERIUM-TUBERCULOSIS INFECTIONS, DIAGNOSIS, REINFECTION, MUTATIONS, PULMONARY, ASSAY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

BACKGROUND Mycobacterium tuberculosis (MTB) is one of the most significant causes of mortality and morbidity. Early diagnose is important especially in multiple drug resistant tuberculosis to avoid transmission. Traditional techniques requires at least one to three weeks for diagnosis of tuberculosis. Diagnostic delays with multiple drug resistant tuberculosis are associated with worse clinical outcomes and increased transmission The Xpert MTB/RIF assay is one of the new diagnostic device for the diagnosis of tuberculosis and rapid detection of rifampicin resistance.