Effects of Risedronate on Alveolar Bone Loss and Angiogenesis: A Stereologic Study in Rats

Özkan Çetinkaya B., Keles G. C., Ayas B., Gurgor P.

JOURNAL OF PERIODONTOLOGY, cilt.79, sa.10, ss.1950-1961, 2008 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 79 Sayı: 10
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1902/jop.2008.080041
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1950-1961
  • Anahtar Kelimeler: Angiogenesis, animal studies, bisphosphonates, osteonecrosis, periodontitis, risedronate, BISPHOSPHONATE-ASSOCIATED OSTEONECROSIS, EXPERIMENTAL PERIODONTITIS, IN-VITRO, TOOTH MOVEMENTS, RESORPTION, ALENDRONATE, JAWS, OSTEOCLASTS, COMPLICATION, PAMIDRONATE
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: The present study was designed to evaluate the effects of risedronate, one of the most potent bisphosphonates, on alveolar bone resorption and angiogenesis in rats with experimental periodontitis to identify dose-response curves and treatment durations that can be therapeutic for periodontal therapy versus those associated with osteonecrosis of the jaws.