Propolis Accelerates the Consolidation Phase in Distraction Osteogenesis

Bereket C., ÖZAN F., Sener I., Tek M., Altunkaynak B. Z., UÇAK SEMİRGİN S., ...Daha Fazla

JOURNAL OF CRANIOFACIAL SURGERY, cilt.25, sa.5, ss.1912-1916, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1097/scs.0000000000000946
  • Dergi Adı: JOURNAL OF CRANIOFACIAL SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1912-1916
  • Anahtar Kelimeler: Distraction osteogenesis, propolis, DEXA, RECOMBINANT HUMAN BONE, CAVALIERI PRINCIPLE, ANTIOXIDANT, COMPLICATIONS, STIMULATION, RABBITS, RELAPSE, CALLUS, VOLUME
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

We evaluated the effect of propolis on new bone formation after distraction osteogenesis (DO). This study examined 3 groups: control group, P100, and P200. Rabbits underwent DO of the left mandible after an osteotomy between the first molar and the mental foramen. Bone mineral content and bone mineral density were evaluated using dual-energy x-ray absorption 1 and 4 weeks after the procedure. The volume of connective tissue and new bone and the number of capillaries were measured using stereologic analysis after the subjects were killed. Dual-energy x-ray absorption showed that the bone mineral content and bone mineral density were higher in the groups treated with propolis by week 4, and these parameters were higher in the P200 group. Stereologic analysis showed no significant differences in connective tissue volume and number of capillaries among the groups. New bone volume was lowest in the P200 group. We concluded that propolis accelerates bone formation and may shorten the consolidation phase with DO.