The effect of curcumin on lung injuries in a rat model induced by aspirating gastrointestinal decontamination agents

Gunaydin M., Guzel A., Guzel A., Alacam H., Salis O., Murat N., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.47, sa.9, ss.1669-1676, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 9
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.jpedsurg.2012.01.076
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1669-1676
  • Anahtar Kelimeler: Acute lung injury, Inflammation, Gastrointestinal decontamination, Activated charcoal, Polyethylene glycol, Curcumin, Rat, RESPIRATORY-DISTRESS-SYNDROME, GLYCOL-ELECTROLYTE SOLUTION, SURFACTANT PROTEIN-A, ACTIVATED-CHARCOAL, CONTROLLED-TRIAL, PULMONARY-EDEMA, NITRIC-OXIDE, INFLAMMATION, FAILURE, PERMEABILITY
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Aspiration is one of the most feared complications of gastrointestinal decontamination procedures with nonabsorbed polyethylene glycol (PEG) solution and activated charcoal (AC). We aimed to investigate the protective effects of curcumin (CUR) on lung injury in rats induced by aspiration of these agents.