The expression of vascular endothelial growth factor in a rat model at destruction and healing stages of periodontal disease

Cetinkaya B. O., Keles G. C., Ayas B., Sakallioglu E. E., Acikgoz G.

JOURNAL OF PERIODONTOLOGY, cilt.78, sa.6, ss.1129-1135, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 6
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1902/jop.2007.060397
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1129-1135
  • Anahtar Kelimeler: angiogenesis, periodontal disease, vascular endothelial growth factor, wound healing, INDUCED GINGIVAL OVERGROWTH, CYCLOSPORINE-A, PERMEABILITY FACTOR, BONE-FORMATION, ANGIOGENESIS, CELLS, PROGRESSION, INHIBITION, TISSUES, ROLES
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: The major role of vascular endothelial growth factor (VEGF), an angiogenic mediator, in promoting the progression or the healing of periodontal disease is still unclear. The aim of this study was to evaluate the VEGF expression in the destruction and healing stages of periodontal disease and to investigate the association between VEGF expression and vascularization with regard to the number and diameters of blood vessels.