The importance of Mediterranean fever gene in familial Mediterranean fever

Kehribar D. Y., Özgen M.

EUROPEAN JOURNAL OF RHEUMATOLOGY, cilt.7, sa.4, ss.173-176, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/eurjrheum.2020.20107
  • Dergi Adı: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.173-176
  • Anahtar Kelimeler: Familial Mediterranean fever, genes, genotype, phenotype, INFLAMMASOME
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: Familial Mediterranean fever (FMF) is the most common autoinflammatory disease characterized by recurrent serositis attacks and fever. The discovery of the Mediterranean fever (MEFV) gene has been a milestone in FMF etiopathogenesis. Our knowledge about the relationship between the MEFV gene and FMF phenotype increases each day. This study aims to investigate the relationship between MEFV gene mutations and the FMF clinical findings of a single-center FMF cohort.