Chromophobe renal cell carcinoma with osseous metaplasia containing fatty bone marrow element: A case report

Kefeli M., Yildiz L., Aydin O., Kandemir B., Yilmaz A. F.

PATHOLOGY RESEARCH AND PRACTICE, cilt.203, sa.10, ss.749-752, 2007 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 203 Sayı: 10
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.prp.2007.06.003
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.749-752
  • Anahtar Kelimeler: chromophobe renal cell carcinoma, calcification, ossification
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

A 27-year-old woman presenting with epigastric pain and dyspepsia was found to have a calcified mass in the upper-middle right kidney. Gross examination of the nephrectomy specimen revealed a 6.5 x 5 x 4 cm. renal tumor with dense calcification and ossification. Histopathological examination of the tumor showed solid, trabecular sheets and nesting of polygonal epithelial cells with abundant cytoplasm and prominent cell border and mature bony tissue enclosing fatty marrow. Renal cell carcinoma is frequently associated with calcification, but ossification is extremely rare. To our knowledge, we report the fourth case of a chromophobe renal cell carcinoma with extensive calcification and ossification. (c) 2007 Elsevier GmbH. All rights reserved.