Antiinflammatory and antioxidant effects of gemcitabine in collagen-induced arthritis model

Dagli A. F., KARATAŞ A., ORHAN C., TUZCU M., Özgen M., ŞAHİN K., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.3, ss.1037-1044, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1606-80
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1037-1044
  • Anahtar Kelimeler: Rheumatoid arthritis, collagen-induced arthritis, gemcitabine, western blotting, RHEUMATOID-ARTHRITIS, DISEASE, NRF2, INFLAMMATION, CELLS, INTERLEUKIN-17, PATHOGENESIS, IMPROVEMENT, METABOLISM, CANCER
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on collagen-induced arthritis (CIA).