Intracystic application of mebendazole solution in the treatment of liver hydatid disease


Erzurumlu K., Şahin M., Selçuk M., Yıldız Ç., Kesim M.

European Surgical Research, cilt.28, sa.6, ss.466-470, 1996 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 6
  • Basım Tarihi: 1996
  • Doi Numarası: 10.1159/000129492
  • Dergi Adı: European Surgical Research
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.466-470
  • Anahtar Kelimeler: Hydatid disease, Intracystic application, Mebendazole
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Mebendazole, a derivate of benzimidazole, is commonly used for the treatment of hydatid disease in patients at high operative risk and/or to prevent secondary hydatidosis. In this study, 2 cases of liver hydatid disease, in which mebendazole was used both orally and for intracystic application are presented. These cases have been treated by percutaneous drainage and videolaparoscopic methods. Mebendazole solution at a concentration of 2.4 µg/ml was injected into the cyst. For a period of 6 months 50 mg/kg/day oral treatment was given. At the end of a 6- to 9-month period, the total recovery was observed. This is the first report of mebendazole pair-treatment in the literature. © 1996 S. Karger AG, Basel.