Neuroprotective Effects of Methylprednisolone and Hypothermia after Experimental Spinal Cord Injury: A Histopathological and Stereological Study


Unal B., Kaplan S., Odaci E., Aslan H., Aksak S., Unal D., ...Daha Fazla

EURASIAN JOURNAL OF MEDICINE, cilt.41, sa.3, ss.169-174, 2009 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 3
  • Basım Tarihi: 2009
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.169-174
  • Anahtar Kelimeler: Cavalieri principle, Hypothermia, Experimental spinal cord injury, Methylprednisolone, Stereology
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: Spinal cord injury is a common trauma among severe accidents in which the spinal cord has been severed; intravenous methylprednisolone and hypothermia are widely used in the treatment of traumatic spinal cord injuries. However, no common consensus has been reached on therapeutic approaches to prevent and reduce disability caused by spinal cord injuries. In this study, the efficacy of methylprednisolone and hypothermia treatments after experimental spinal cord injury made by dynamic weight-drop model in rabbits was investigated.