Effects of Intraperitoneal Zoledronic Acid Administration on Cerebral Vasospasm Following Experimental Subarachnoid Hemorrhage in Rats

Ulus A., Celik O., Arslanhan A., KAYA Ö. T., ÖZKAN M., YILMAZ GÖLER A. M., ...Daha Fazla

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.32, sa.3, ss.450-460, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 3
  • Basım Tarihi: 2015
  • Dergi Adı: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.450-460
  • Anahtar Kelimeler: Cerebral vasospasm, subarachnoid hemorrhage, vascular morphometry, neurological outcome, zoledronic acid, NITRIC-OXIDE SYNTHASE, MESSENGER-RNA, UP-REGULATION, RHO-KINASE, BISPHOSPHONATE, SIMVASTATIN, INVOLVEMENT, INHIBITION, AGONIST, STATINS
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Early brain injury and cerebral vasospasm are major factors determining outcome for patients who experience subarachnoid hemorrhage (SAH). This study was performed to investigate the potential therapeutic effects of zoledronic acid on cerebral vasospasm in an experimental SAH model.