Effect of 900 MHz radiofrequency radiation on oxidative stress in rat brain and serum

Bilgici B., Akar A., Avcı B., Tunçel Ö. K.

ELECTROMAGNETIC BIOLOGY AND MEDICINE, sa.1, ss.20-29, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3109/15368378.2012.699012
  • Dergi Adı: ELECTROMAGNETIC BIOLOGY AND MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.20-29
  • Anahtar Kelimeler: Electromagnetic radiation, Oxidative stress, Antioxidants, Garlic, ELECTROMAGNETIC-RADIATION, NITRIC-OXIDE, CELLULAR PHONES, ACUTE EXPOSURE, MOBILE PHONE, FIELD, MALONDIALDEHYDE, ANTIOXIDANTS, CANCER
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

The increasing use of mobile telephones raises the question of possible adverse effects of the electromagnetic fields (EMF) that these phones produce. In this study, we examined the oxidative stress in the brain tissue and serum of rats that resulted from exposure to a 900-MHz EMF at a whole body average specific absorption rate (SAR) of 1.08 W/kg for 1 h/day for 3 weeks. We also examined the antioxidant effect of garlic powder (500 mg/kg/day) given orally to EMF-exposed rats. We found that malondialdehyde (MDA) (p < 0.001) and advanced oxidation protein product (AOPP) (p < 0.05) increased in rat brain tissue exposed to the EMF and that garlic reduced these effects (p < 0.05). There was no significant difference in the nitric oxide (NO) levels in the brain. Paraoxonase (PON) was not detected in the brain. There was a significant increase in the levels of NO (p < 0.001) detected in the serum after EMF exposure, and garlic intake did not affect this increase in NO. Our results suggest that there is a significant increase in brain lipid and protein oxidation after electromagnetic radiation (EMR) exposure and that garlic has a protective effect against this oxidative stress.