Serum amyloid-a may be an early marker in diagnosis of preterm premature rupture of membrane and chorioamnionitis

KAYABAŞ H., BILDIRCIN F. D., AVCI B., KARLI P., Özdemir A. Z., ALPER T.

Annals of Medical Research, cilt.26, sa.12, ss.2802-2806, 2019 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 12
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5455/annalsmedres.2019.11.751
  • Dergi Adı: Annals of Medical Research
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.2802-2806
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Aim: To determine the efficiency of serum amyloid-A (SAA) in predicting preterm premature rupture of membrane (PPROM) andchorioamnionitis in risky cases.Study Design: The study consists of 20 women 26-37 weeks of pregnancy who had PPROM and 20 pregnant women without waterbreaks. Levels of SAA were determined in maternal venous and umbilical cord blood.Results: SAA values in cord blood and venous blood of mothers with PPROM were higher than in the control group (p<0,05). SAAvalues in the patients with clinical chorioamnionitis (n=9) were significantly higher (p<0,05) than both PPROM patients withoutchorioamnionitis (n=11) and the control group (n=20).Conclusion: In women at risk for PPROM in whom diagnosis cannot be established, blood SSA levels can be used as a marker. IncreasedSAA values in pregnant women with PPROM who were conservatively treated were considered a marker for chorioamnionitis.