The Effect of Platelet Rich Plasma on Wound Healing in the Repair of Experimental Penile Fractures

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Duz E., Beger B., SAĞLAM K., Yildirim S.

INDIAN JOURNAL OF ANIMAL RESEARCH, cilt.56, sa.1, ss.65-71, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.18805/ijar.b-1363
  • Dergi Adı: INDIAN JOURNAL OF ANIMAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.65-71
  • Anahtar Kelimeler: Penile fracture, Platelet-rich plasma, Rat, GROWTH-FACTORS, GEL, REGENERATION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background: Penile fractures are caused by the rupture of the tunica albuginea and the underlying layers of corpus cavernosum as a result of the exposure of the erect penis to blunt trauma. Although conservative treatment methods have been recommended in former studies, recent studies favor early surgical options. Platelet-rich plasma (PRP) is a blood product rich in cytokines and several growth factors, obtained from the patient's own blood commonly used to stimulate healing in acute and chronic wound treatments. The efficiency of homologous PRP treatment in rats with penile fractures have been assessed in terms of clinical manifestation and histopathological findings in the present study.