Pentraxin-3 level in subarachnoid haemorrhage: Is it a prognostic factor?

Katı C., Yardan T., Akdemir H. U., Duran L., Aydin K., Yilman M.

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, cilt.70, sa.6, ss.984-988, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5455/jpma.3194
  • Dergi Adı: JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.984-988
  • Anahtar Kelimeler: Pentraxin-3, Subarachnoid haemorrhage, Glasgow coma scale, Fisher scale, Glasgow outcome scale, CEREBRAL VASOSPASM, CEREBROSPINAL-FLUID, MANAGEMENT, TIME
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: The current study was planned to investigate the relationship of serum level of pentraxine-3 with various clinical and neurological scales and scores.. Methods: The prospective case -control study was conducted at the Emergency Department of the Ondokuz Mayis University, Samsun, Turkey, from March 2013 to June 2014, and comprised subarachnoid haemorrhage patients and healthy. Pentraxine-3levels were measured from serum samples and compared with sub -groups of the various scales and scores used in the study. Data was analysed using SPSS 15. Results: Of the 77 subjects, 40(52%) were patients and 37(48%) were controls. Pentraxine-3levels in the cases were significantly higher than the controls (p<0.001). Among the cases, pentraxine-3level of the Glasgow Coma Scale sub -group was significantly different between the severe and mild categories (p=0.048). Likewise, pentraxine-3 levels were significantly different in terms of Fisher scale in patients with minor haemorrhage compared to those with massive haemorrhage (p=0.026). Also, pentraxine-3 levels were significantly higher in patients who died compared to those who fully recovered (p=0.042). Conclusion: There was found to be a relationship between pentraxine-3 level and the clinical severity of subarachnoid haemorrhage patients.