Examination of the Relationship Between Average Plaque Volume and Clinical and Demographic Characteristics in Multiple Sclerosis Patients Using a Stereological Method

Terzi M., Yilmaz E., Şahin B., Kaplan S., Onar M.

INTERNATIONAL JOURNAL OF NEUROSCIENCE, cilt.121, sa.7, ss.366-372, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 121 Sayı: 7
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3109/00207454.2011.560313
  • Dergi Adı: INTERNATIONAL JOURNAL OF NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.366-372
  • Anahtar Kelimeler: Multiple sclerosis, prognosis, stereology, 3-DIMENSIONAL MRI, ATROPHY, BRAIN, DISABILITY, INFLAMMATION, PREDICTION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Aim: The objectives of this study were to investigate the lesion load on brain magnetic resonance images and the volume of different cerebral anatomical structures, in patients with a diagnosis of definite multiple sclerosis, using a stereological method. Methods: Fifty patients diagnosed with multiple sclerosis were included in the study. The volume fractions of the hemispheres, lateral ventricles, cerebellum, brain stem, and plaque volumes within the total brain volume were estimated. Results: The mean plaque volume was 0.83 +/-+/- 0.14 cm