Can empirical hypertonic saline or sodium bicarbonate treatment prevent the development of cardiotoxicity during serious amitriptyline poisoning? Experimental research

Paksu, Muhammet; Zengin, Halit; Ilkaya, Fatih; Paksu, Sule; Guzel, Hasan; Ucar, Durmus; Uzun, Adem; Alacam, Hasan; Duran, Latif; Murat, Naci; Guzel, Ahmet

doi:10.5830/cvja-2015-014

Can empirical hypertonic saline or sodium bicarbonate treatment prevent the development of cardiotoxicity during serious amitriptyline poisoning? Experimental research

Atıf İçin Kopyala

Paksu M. S., Zengin H., Ilkaya F., Paksu S., Guzel H., Ucar D., ...Daha Fazla

CARDIOVASCULAR JOURNAL OF AFRICA, cilt.26, sa.3, ss.134-139, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 3
Basım Tarihi: 2015
Doi Numarası: 10.5830/cvja-2015-014
Dergi Adı: CARDIOVASCULAR JOURNAL OF AFRICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.134-139
Anahtar Kelimeler: amitriptyline, poisoning, cardiotoxicity, sodium bicarbonate, hypertonic saline, TRICYCLIC ANTIDEPRESSANT OVERDOSE, INDUCED CARDIOVASCULAR TOXICITY, CHARCOAL HEMOPERFUSION, INTOXICATION, CHILDREN, RATS, HYPERVENTILATION, HYPONATREMIA, HYPOTENSION, EMERGENCY
Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objective: The aim of this experimental study was to investigate whether hypertonic saline or sodium bicarbonate administration prevented the development of cardiotoxicity in rats that received toxic doses of amitriptyline.