Marek's disease virus in vaccinated poultry flocks in Turkey: its first isolation with molecular characterization

Özan E., Müftüoğlu B., Sahindokuyucu I., Kuruçay H. N., İnal S., Kuruca Şahbazoğlu N., ...Daha Fazla

ARCHIVES OF VIROLOGY, cilt.166, sa.2, ss.559-569, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 166 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s00705-020-04943-6
  • Dergi Adı: ARCHIVES OF VIROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.559-569
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Marek's disease (MD) is an important disease of avian species and a potential threat to the poultry industry worldwide. In this study, 16 dead commercial chickens from flocks with suspected MD were necropsied immediately after death. Pathological findings were compatible with MD, and gallid alphaherpesvirus 2 was identified in PCR of spleen samples. Virus isolation was performed in primary cell culture, and partial sequencing of the meq gene of the isolate revealed >99% nucleotide sequence identity to virulent and very virulent plus strains from a number of European countries, placing it in the same subclade of clade III as two virulent Italian strains and a very virulent plus Polish strain as well as virulent strains of geese and ducks. The data reported here indicate that a virulent strain of Marek's disease virus is circulating in Turkey and has not been stopped by the current national vaccination programme.